British Air Force Typhoon FGR4s have joined forces with France's air force in a combined operation targeting an hidden munitions depot in Syria employed by the Daesh militant organization, according to the UK's MoD.
The location, located using intelligence, was thought to be housing weapons and explosive materials, the statement said, and was located in mountainous terrain just above the ancient city of Palmyra in the heart of Syria.
"The RAF jets utilized precision-guided Paveway IV munitions to strike a number of access tunnels down to the facility... initial indications are that the target was engaged successfully," the MoD said.
There was no indication of any civilian impact in the attack on Saturday evening and each participating jet returned to base without incident, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager tanker plane.
IS - alternatively referred to as Daesh - imposed militant control over significant areas in Syria and Iraq until 2019.
"This strike underscores British leadership, and determination to stand shoulder to shoulder with our partners, to eliminate any revival of Daesh and their harmful and extremist ideologies in the Middle East," UK Defence Secretary the minister stated.
British military aircraft have conducted surveillance missions over Syrian airspace to "prevent any attempted resurgence" of Islamic State after its military defeat at the battle of Baghuz in 2019, the ministry said.
"I extend gratitude to every member of the UK armed forces who took part in this strike for their expertise and their courage," the Defence Secretary commented. "Including them were a great many UK service members stationed over the holidays. This action, to eliminate terrorist threats who pose a risk to our safety, demonstrates how UK forces are ready to step up, all year round, keeping Britain secure domestically and influential overseas."
Last December, the United States armed forces executed what it termed a "major assault" against Islamic State objectives in the country, after an ambush killed two American soldiers and a civilian linguist in the Palmyra area.
The United Nations says Islamic State still boasts between 5,000 and 7,000 fighters in both countries.
